David Gerrold, a prolific American author, and screenwriter, summarizes the progress of the last 120 years when he observes, “In the 20th century, we had a century where at the beginning of the century, most of the world was agricultural and industry was very primitive. At the end of that century, we had men in orbit, we had been to the moon, we had people with cell phones and color televisions and the Internet and amazing medical technology of all kinds.”
The meteoric acceleration of “amazing medical technology of all kinds” continues today, and the laboratories at NIST, the National Institute of Standards and Technology, are significant players in this progress.
The benefits of NIST’s technology research come to the marketplace when businesses license NIST’s patents, and this article introduces three biomedical technologies in the field of phase-contrast X-ray imaging that are available for licensing.
These patents are the product of more than two decades of research in electrodeposition by Daniel Josell and Thomas P. Moffat of the Functional Nanostructured Materials Group in the Materials Science and Engineering Division of NIST’s Material Measurement Laboratory.
X-ray technology has always been adept at imaging bones, but imaging soft tissue is more complicated. The overall issue addressed by these inventions is the improvement of X-ray phase contrast imaging technologies for soft tissue imaging without the injection of contrast agents.
The first of the technologies available for licensing is a chemistry that improves gold filling of features recessed into substrate surfaces, including, but not limited to, features in gratings used in phase contrast imaging. Drs. Moffat and Josell invented a method to fill features patterned into the surfaces of conducting substrates, or substrates such as silicon wafers with metalized surfaces, usin ..
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