Researchers Analyze THC in Breath of Cannabis Smokers

Researchers Analyze THC in Breath of Cannabis Smokers

The CU Boulder mobile pharmacology lab where study participants provided breath samples before and after smoking cannabis in their homes.


Credit: Courtesy of Cinnamon Bidwell, University of Colorado Boulder


Most states in the U.S. allow people to use cannabis for medical or recreational purposes. Yet all states want their roadways to be safe. A breathalyzer that can accurately identify people who recently smoked cannabis might help them keep impaired drivers off the road — if such a device existed. 


But developing a breathalyzer for cannabis is far more difficult than for alcohol, which people exhale in large amounts when drinking. In contrast, the intoxicating component of cannabis, called THC, is thought to be carried inside aerosol particles that people exhale. The total volume of aerosols can be very small, making it difficult to accurately measure their THC content. Currently, there is no standard method for doing this.


Now, researchers at the National Institute of Standards and Technology (NIST) and the University of Colorado Boulder have conducted a study in which they collected breath samples from people both before and after they smoked high-THC cannabis, aka marijuana, and used laboratory instruments (not a handheld device) to measure the amount of THC in their breath. The goal of this study, published in the Journal of Breath Research, was to begin developing a protocol that yields reproducible results — a necessary step toward a reliable, validated field-based method.


The samples collected before people smoked were important because THC can persist in the bodies of people who frequently use cannabis for a month or more, ..

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