NIST Researchers Use Novel Method to Understand the Molecular Underpinnings of a Tumorlike Disease Affecting Coral Reefs

NIST Researchers Use Novel Method to Understand the Molecular Underpinnings of a Tumorlike Disease Affecting Coral Reefs


A coral disease called growth anomalies (GAs) is depicted here in the coral species Porites compressa, a reef-building species found off the coast of Hawaii. GAs can cause tumorlike protrusions that affect both the coral skeleton and its soft tissues.



Credit: E. Andersson/NIST



Coral reefs are a favorite spot for scuba divers and are among the world’s most diverse ecosystems. For example, the Hawaiian coral reefs, known as the “rainforests of the sea,” host over 7,000 species of marine animals, fishes, birds and plants. But coral reefs are facing serious threats, including a number of diseases that have been linked to human activity.


To understand the connection between human activity and a type of tumorlike disease called growth anomalies (GAs), researchers at the National Institute of Standards and Technology (NIST) have collaborated with the U.S Geological Survey (USGS) and the National Oceanic and Atmospheric Administration (NOAA) to use an emerging molecular profiling method to identify 18 small molecules that promise to help them better understand the series of molecular reactions that lead to the disease.


GAs affect both the coral skeleton and its soft tissues. Scientists don’t know the cause of the disease or how it spreads but have hypothesized that there is a strong correlation between GA prevalence in coral colonies and human population density nearby. 


Almost all types of corals are made of hundreds to millions of individual soft-bodied animals called polyps. The polyps secrete calcium carbonate to form a hard skeleton that lays the foundation for the coral colony. GAs affect co ..

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