NIST has established a Health Assessment Measurements Quality Assurance Program (HAMQAP), in collaboration with the National Institutes of Health Office of Dietary Supplements, to help natural products, food, and clinical laboratories demonstrate measurement competence. The accuracy and precision of measurements made by natural products and food labs is important so that manufacturers and consumers are confident in the claims on nutrition and ingredients labels, and to comply with regulations from the U.S. Food and Drug Administration. The accuracy of measurements made in clinical labs is important so that patients are properly diagnosed and receive the correct treatments. In some clinical trials, researchers test both consumed products and their metabolized outputs in body fluids like blood and urine to better understand how consumption of a food or natural product can influence a person’s health status.
For many decades, NIST has supported these communities with reference materials that labs can use to check their analytical methods; This program is another form of measurement support.
Labs participating in HAMQAP can choose to conduct a variety of studies, from nutritional and toxic elements, to vitamins and fatty acids, to protein source identification. When possible, materials representing human intakes, such as foods and dietary supplements, are paired with materials that represent their metabolic products, such as substances in urine, blood, serum, plasma, and human milk. While participants are not required to select all analytes or all materials, pairing them gives NIST the opportunity to better understand challenges across the complete spectrum of tests of human health.
Participants in NIST quality assurance programs analyze the materials and share their results with NIST. In return, test labs learn how their measurement results compare to other participants in the study, and to the rigorously measured and agreed upon value, when ava ..
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