The Special Fridges Behind The COVID-19 Vaccine, Why It’s Surprisingly Difficult To Be That Cool

The Special Fridges Behind The COVID-19 Vaccine, Why It’s Surprisingly Difficult To Be That Cool

One of the big stories last week was the announcement of results from clinical trials that suggest a new COVID-19 vaccine from the German companies Pfizer and BioNTech is strongly effective in providing immunity from the virus. In the midst of what is for many countries the second spike of the global pandemic this news has been received with elation as well as becoming the subject of much political manoeuvring.


While we currently have two vaccine candidates with very positive testing results, one of the most interesting things for us is the need to keep doses of the Pfizer/BioNTech vaccine extremely cold until they are administered. Let’s dig into details of the refrigeration problem at hand.

Special Fridges for -80 °C (-112 °F)



This rather unappetising view is the scar on my arm from my smallpox vaccination. You probably don’t have one of these if you’re young, because vaccinations like this one across whole populations successfully eradicated smallpox worldwide by 1980.

This particular vaccine must be refrigerated at -80 Celsius until it is ready for use. This presents a significant problem for any mass vaccination programme, because while -80 degree freezers are a done deal in terms of manufacture they are not commonly to be found in community healthcare. Labs and major hospitals may have them, but we’re told that even in a developed country the general practitioners who will be tasked with administering the vaccine have until now had little need for one. If this presents a problem in a place with significant resources then it is magnified significantly in less wealthy regions of the world, bec ..

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